Hotels in FloridaIndependent guide

Hilton Jacksonville at Mayo Clinic near Beaches

Isle of Palms South, Florida

4-star class on Booking.com

Comfortable rooms and a pool in Isle of Palms South

Check availability
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When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.

14 room types Wi-Fi Parking Pool Breakfast A/C Restaurant
Welcome

About Hilton Jacksonville at Mayo Clinic near Beaches

Set in Isle of Palms South, Florida, Hilton Jacksonville at Mayo Clinic near Beaches is a four-star hotel. It offers a fitness center, a swimming pool and an on-site restaurant. Room types include the King Room with Chaise and the Queen Room with Two Queen Beds.

Is it right for you?

Who it suits

Expect a four-star hotel.

Best for

  • Travelers who want a pool
  • Families with children
  • Road trips & drive-up convenience
  • Business travelers

What a stay costs

Prices change by date and room. The booking site shows the total for your dates before you pay; check whether it includes taxes and local fees.

Rooms & rates

Choose from 14 room types — including the King Room with Chaise, Queen Room with Two, Queen Room with Two Queen Beds - Hearing Access.

Take a dip in the pool

The pool is a welcome spot to cool off and unwind during your stay.

The location

Hilton Jacksonville at Mayo Clinic near Beaches is in Isle of Palms South, Florida.

Rooms & suites

The View availability buttons open this hotel's page on Booking.com · Affiliate link

King Room with Chaise

30.0 m² · 1 king bed

  • 1 room
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Coffee machine

Queen Room with Two Queen Beds

32.0 m² · 2 queen beds

  • 1 room
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Coffee machine

Queen Room with Two Queen Beds - Hearing Access

32.0 m² · 2 queen beds

  • 1 room
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Coffee machine

King Room - Hearing Access

30.0 m² · 1 king bed

  • 1 room
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Free Wifi

King Room with Water View

30.0 m² · 1 king bed

  • 1 room
  • View
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

King Room with Roll-In Shower and Water View - Mobility Accessible

30.0 m² · 1 king bed

  • 1 room
  • View
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

Queen Room with Two Queen Beds and Water View

32.0 m² · 2 queen beds

  • 1 room
  • View
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

Queen Room with Two Queen Beds and Bath Tub - Water View/Mobility Accessible

32.0 m² · 2 queen beds

  • 1 room
  • View
  • Bath
  • Air conditioning
  • Attached bathroom

Deluxe King Room with Sofa and Water View

41.0 m² · 1 king bed

  • 1 room
  • View
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

Deluxe King Room with Roll-In Shower and Water View - Mobility Accessible

41.0 m² · 1 king bed

  • 1 room
  • View
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

Junior King Suite with Roll-In Shower - Mobility Accessible

45.0 m² · 1 king bed

  • Private suite
  • Bath
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV

Junior King Suite with Roll-In Shower - Mobility/Hearing Accessible

45.0 m² · 1 king bed

  • Private suite
  • Bath
  • Air conditioning
  • Flat-screen TV
  • Free Wifi

Corner Junior King Suite with Roll-In Shower - Mobility Accessible

58.0 m² · 1 king bed

  • Private suite
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Free Wifi

Junior King Suite - Open Floor Plan

45.0 m² · 1 king bed

  • Private suite
  • Air conditioning
  • Attached bathroom
  • Flat-screen TV
  • Free Wifi

Photos of Hilton Jacksonville at Mayo Clinic near Beaches

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Standout features

Outdoor Pool
On-site Dining
Breakfast
Fitness Center
Bar & Lounge
Parking

Amenities at Hilton Jacksonville at Mayo Clinic near Beaches

On site

  • Pool
  • Gym
  • Wi-Fi
  • Restaurant
  • Bar
  • 24-hour front desk

In the rooms

  • Air conditioning
  • Balcony or terrace

Location

4745 Transformation Way, Isle of Palms South, FL 32224, United States

Get directions

Good to know

Air conditioningAvailable
Front desk24 hours
MealsBreakfast available
AccessibilityWheelchair accessible
Languages spokenEnglish

House rules

Check-in is from 4 pm, and check-out is by 11 am. Cancellation and prepayment terms vary by room and rate, and the booking site shows them before you pay.

Frequently asked

Does Hilton Jacksonville at Mayo Clinic near Beaches have a pool?

Yes, Hilton Jacksonville at Mayo Clinic near Beaches has a pool for guests.

What amenities does Hilton Jacksonville at Mayo Clinic near Beaches offer?

Hilton Jacksonville at Mayo Clinic near Beaches offers Room service, Beach chairs/Loungers, 24-hour front desk, Fitness center, Outdoor swimming pool, Restaurant, Free Wifi, Express check-in/out, Daily housekeeping, Breakfast, Outdoor fireplace, and Outdoor furniture.

What room types are available at Hilton Jacksonville at Mayo Clinic near Beaches?

Room options include King Room with Chaise, Queen Room with Two, Queen Room with Two Queen Beds - Hearing Access, King Room - Hearing Access, King Room with Water View.

Where is Hilton Jacksonville at Mayo Clinic near Beaches located?

Hilton Jacksonville at Mayo Clinic near Beaches is located in Isle of Palms South, Florida, at 4745 Transformation Way.

Plan your stay

Thinking about Hilton Jacksonville at Mayo Clinic near Beaches?

Check availability
Live prices for your dates on Booking.com · Affiliate link

When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.

Contact
Address4745 Transformation Way, Isle of Palms South, FL 32224, United States
Book online
Check availability
Live prices for your dates on Booking.com · Affiliate link

When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.