Hilton Jacksonville at Mayo Clinic near Beaches
4-star class on Booking.com
Comfortable rooms and a pool in Isle of Palms South
Live prices for your dates on Booking.com · Affiliate link
When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.
About Hilton Jacksonville at Mayo Clinic near Beaches
Set in Isle of Palms South, Florida, Hilton Jacksonville at Mayo Clinic near Beaches is a four-star hotel. It offers a fitness center, a swimming pool and an on-site restaurant. Room types include the King Room with Chaise and the Queen Room with Two Queen Beds.
Who it suits
Expect a four-star hotel.
Best for
- Travelers who want a pool
- Families with children
- Road trips & drive-up convenience
- Business travelers
What a stay costs
Prices change by date and room. The booking site shows the total for your dates before you pay; check whether it includes taxes and local fees.
Rooms & rates
Choose from 14 room types — including the King Room with Chaise, Queen Room with Two, Queen Room with Two Queen Beds - Hearing Access.
Take a dip in the pool
The pool is a welcome spot to cool off and unwind during your stay.
The location
Hilton Jacksonville at Mayo Clinic near Beaches is in Isle of Palms South, Florida.
Rooms & suites
The View availability buttons open this hotel's page on Booking.com · Affiliate link
King Room with Chaise
30.0 m² · 1 king bed
- 1 room
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Coffee machine
Queen Room with Two Queen Beds
32.0 m² · 2 queen beds
- 1 room
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Coffee machine
Queen Room with Two Queen Beds - Hearing Access
32.0 m² · 2 queen beds
- 1 room
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Coffee machine
King Room - Hearing Access
30.0 m² · 1 king bed
- 1 room
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Free Wifi
King Room with Water View
30.0 m² · 1 king bed
- 1 room
- View
- Air conditioning
- Attached bathroom
- Flat-screen TV
King Room with Roll-In Shower and Water View - Mobility Accessible
30.0 m² · 1 king bed
- 1 room
- View
- Air conditioning
- Attached bathroom
- Flat-screen TV
Queen Room with Two Queen Beds and Water View
32.0 m² · 2 queen beds
- 1 room
- View
- Air conditioning
- Attached bathroom
- Flat-screen TV
Queen Room with Two Queen Beds and Bath Tub - Water View/Mobility Accessible
32.0 m² · 2 queen beds
- 1 room
- View
- Bath
- Air conditioning
- Attached bathroom
Deluxe King Room with Sofa and Water View
41.0 m² · 1 king bed
- 1 room
- View
- Air conditioning
- Attached bathroom
- Flat-screen TV
Deluxe King Room with Roll-In Shower and Water View - Mobility Accessible
41.0 m² · 1 king bed
- 1 room
- View
- Air conditioning
- Attached bathroom
- Flat-screen TV
Junior King Suite with Roll-In Shower - Mobility Accessible
45.0 m² · 1 king bed
- Private suite
- Bath
- Air conditioning
- Attached bathroom
- Flat-screen TV
Junior King Suite with Roll-In Shower - Mobility/Hearing Accessible
45.0 m² · 1 king bed
- Private suite
- Bath
- Air conditioning
- Flat-screen TV
- Free Wifi
Corner Junior King Suite with Roll-In Shower - Mobility Accessible
58.0 m² · 1 king bed
- Private suite
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Free Wifi
Junior King Suite - Open Floor Plan
45.0 m² · 1 king bed
- Private suite
- Air conditioning
- Attached bathroom
- Flat-screen TV
- Free Wifi
Standout features
Amenities at Hilton Jacksonville at Mayo Clinic near Beaches
On site
- Pool
- Gym
- Wi-Fi
- Restaurant
- Bar
- 24-hour front desk
In the rooms
- Air conditioning
- Balcony or terrace
Good to know
House rules
Check-in is from 4 pm, and check-out is by 11 am. Cancellation and prepayment terms vary by room and rate, and the booking site shows them before you pay.
Frequently asked
Does Hilton Jacksonville at Mayo Clinic near Beaches have a pool?
Yes, Hilton Jacksonville at Mayo Clinic near Beaches has a pool for guests.
What amenities does Hilton Jacksonville at Mayo Clinic near Beaches offer?
Hilton Jacksonville at Mayo Clinic near Beaches offers Room service, Beach chairs/Loungers, 24-hour front desk, Fitness center, Outdoor swimming pool, Restaurant, Free Wifi, Express check-in/out, Daily housekeeping, Breakfast, Outdoor fireplace, and Outdoor furniture.
What room types are available at Hilton Jacksonville at Mayo Clinic near Beaches?
Room options include King Room with Chaise, Queen Room with Two, Queen Room with Two Queen Beds - Hearing Access, King Room - Hearing Access, King Room with Water View.
Where is Hilton Jacksonville at Mayo Clinic near Beaches located?
Hilton Jacksonville at Mayo Clinic near Beaches is located in Isle of Palms South, Florida, at 4745 Transformation Way.
Hotels near Hilton Jacksonville at Mayo Clinic near Beaches
- Residence Inn By Marriott Jacksonville-Mayo Clinic Area· Isle of Palms South · 0.6 mi
- Holiday Inn Express & Suites Jacksonville South East - Medical Center Area by IHG· Isle of Palms South · 1.4 mi
- Hampton Inn & Suites Jacksonville Beach Boulevard/Mayo Clinic· Isle of Palms South · 2.0 mi
- TownePlace Suites by Marriott Jacksonville East· Jacksonville · 2.1 mi
- Hampton Inn Jacksonville Ponte Vedra· Jacksonville Beach · 2.7 mi
- Holiday Inn Express Jacksonville Beach by IHG· Jacksonville Beach · 3.1 mi
- Element by Marriott Jacksonville Beach· Jacksonville Beach · 3.6 mi
- Four Points by Sheraton Jacksonville Beachfront· Jacksonville Beach · 3.7 mi
Live prices for your dates on Booking.com · Affiliate link
When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.











